Molecular Signalling Pathway in Sinonasal Polyposis- The Role of MAPK/JNK, P13K/mTOR and LC3 pathways in the Pathogenesis of Sino-Nasal Polyposis

Abstract

Nasal polyps are benign masses arising from the mucous membranes of the nose and paranasal sinuses. Despite the significant morbidity of this recurrent disease the underlying central mechanisms regarding the pathogenesis of sinonasal polyposis are complex and poorly understood.